ABSTRACT
Skin adnexal tumours are a large group of benign and malignant tumours that arise from pluripotent stem cells and differentiate toward one or more adnexal structures. So, quite often they may exhibit more than one line of differentiation (hybrid tumours). Moreover, they are uncommon, clinically nonspecific, and remain a diagnostic challenge to surgeons and pathologists alike. The present study is aimed at analysing the histopathological profile of skin adnexal tumours in a hospital based population in Manipur.METHODSThe present study is a retrospective analysis conducted over a period of 3 years from January 2017 to December 2019 in the Department of Pathology, Jawaharlal Institute of Medical Sciences, Manipur, India. Specimens were fixed in formalin, paraffin embedded and stained with haematoxylin and eosin for histopathologic analysis.RESULTSA total of 34 cases of skin adnexal tumours were reported in the Department of Pathology, JNIMS, Imphal, over a period of 3 years out of which 94% (32/34) of the total cases were benign tumours and 5.88% (2/34) were malignant tumours. Tumours with hair follicle differentiation comprised the largest group (44.1%). Pilomatrixoma was the most common tumour followed by Nevus Sebaceous. Both malignant adnexal tumours were sebaceous carcinomas.CONCLUSIONSSkin adnexal tumours are uncommon tumours with most of them being benign tumours and there is a low incidence of malignant tumours. Malignant tumours although rare, need to be diagnosed accurately since they can be aggressive with distant and nodal metastasis. Histopathologic examination remains the gold standard in diagnosing these rare lesions.